Systemic HormonesUnregulated/Therapeutic
Oxytocin
Synonyms: Pitocin, Syntocinon, Bonding Hormone
Sequence: H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
History & Discovery Timeline
Oxytocin was sequenced and synthesized in 1953 by Vincent du Vigneaud, marking the first time a polypeptide hormone was synthesized, earning him a Nobel Prize.
What it is: It is a cyclic nonapeptide hormone and neuropeptide. It is classified under Tissue Repair/Immune (neuroendocrine).
Proposed Mechanisms & Research Findings: It acts as an agonist at the oxytocin receptor, modulating social behavior, uterine contractions, lactation, and anti-inflammatory pathways.
Regulatory & Safety Status: It is FDA approved for labor induction and postpartum hemorrhage (brand name Pitocin). Sourcing must be conducted under medical supervision.
Athletic & Anti-Doping Status: It is not prohibited by WADA, as it does not improve athletic performance.
Understanding Oxytocin Key Facts
Primary Target System:NEUROENDOCRINE
Residue Count / Length:11 Amino Acids
Primary Action & Category:Oxytocin Receptor Agonist (Systemic Hormones)
Primary Receptors:Oxytocin Receptor (OXTR)
Figure 1: Detailed molecular mechanism pathways of Oxytocin (click to enlarge).